ACS Legacy Archives

Tap into research that is still assisting breakthroughs today

Some of the world’s most cutting-edge discoveries are still being influenced by yesterday’s research. Get the ACS Legacy Archives and equip your researchers with 117 years of content that continues to be in high demand. The ACS Legacy Archives includes all ACS journal content published up to and including 1995. That includes more than 460,000 articles spanning more than a century of scientific research. 

The ACS Legacy Archives is available to institutions via annual or multi-year lease, or available to purchase outright. Pricing is based on usage and institution tier.

Get access or contact your sales representative directly to review all acquisition options.

Why choose ACS Legacy Archives?


  • The concepts captured in the ACS Legacy Archives are applied in new ways every day. References to the Archives still appear in new patent applications, including patents for some of today’s most-prescribed drugs.
  • ACS Legacy Archives integration into the ACS Publications platform provides a single search tool with enhanced discoverability and full-text searching, making it easier than ever to locate important journal data.
  • ACS’s stellar reputation is built on the decades of reputable research contained in the ACS Legacy Archives. This collection provides a lasting, searchable, digital historic record for all ACS journals covered, helping you save physical space.
Below you will find a selection of the most cited articles from the ACS Legacy Archives, which are still getting referenced in 2024. These articles represent impactful research continuing to influence and drive new discoveries.

HEALTHCARE

Abstract image for Medicinal Chemistry
ANALYTICAL CHEMISTRY

Colorimetric Method for Determination of Sugars and Related Substances

Michel. DuBois, K. A. Gilles, J. K. Hamilton, P. A. Rebers, and Fred. Smith
Abstract image for Medicinal Chemistry
ANALYTICAL CHEMISTRY

Smoothing and Differentiation of Data by Simplified Least Squares Procedures

Abraham. Savitzky and M. J. E. Golay
Abstract image for Medicinal Chemistry
ANALYTICAL CHEMISTRY

Reaction Kinetics in Differential Thermal Analysis

H. E. Kissinger

MATERIALS SCIENCE

Abstract image for Material Science
JACS

The Temperature Dependence of Relaxation Mechanisms in Amorphous Polymers and Other Glass-forming Liquids

Malcolm L. Williams, Robert F. Landel, and John D. Ferry
Abstract image for Material Science
MACROMOLECULES

Connection between Polymer Molecular Weight, Density, Chain Dimensions, and Melt Viscoelastic Properties

L. J. Fetters, D. J. Lohse, D. Richter, T. A. Witten, and A. Zirkel
Abstract image for Material Science
ANALYTICAL CHEMISTRY

Performance Characteristics of Diffusion Gradients in Thin Films for the in Situ Measurement of Trace Metals in Aqueous Solution

Hao. Zhang and William. Davison

AGRICULTURE, FOOD & ENVIRONMENT

Abstract image for Environment
JOURNAL OF AGRICULTURAL & FOOD CHEMISTRY

Determination of the degree of hydrolysis of food protein hydrolysates by trinitrobenzenesulfonic acid

Jens Adler-Nissen
Abstract image for Environment
JOURNAL OF AGRICULTURAL & FOOD CHEMISTRY

Rapid, Sensitive, and Specific Thiobarbituric Acid Method for Measuring Lipid Peroxidation in Animal Tissue, Food, and Feedstuff Samples

Nickos A. Botsoglou, Dimitrios J. Fletouris, Georgios E. Papageorgiou, Vassilios N. Vassilopoulos, Antonios J. Mantis, and Antonios G. Trakatellis
Abstract image for Environment
THE JOURNAL OF PHYSICAL CHEMISTRY

Size Effects on the Photophysical Properties of Colloidal Anatase TiO2 Particles: Size Quantization versus Direct Transitions in This Indirect Semiconductor?

N. Serpone, D. Lawless, and R. Khairutdinov

BIOTECH & PHARMA

Abstract image for BioChemistry
JOURNAL OF MEDICINAL CHEMISTRY

Aromatic substituent constants for structure-activity correlations

Corwin Hansch, Albert Leo, Stefan H. Unger, Ki Hwai Kim, Donald Nikaitani, and Eric J. Lien
Abstract image for BioChemistry
JOURNAL OF MEDICINAL CHEMISTRY

Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

B. E. Evans, K. E. Rittle, M. G. Bock, R. M. DiPardo, R. M. Freidinger, W. L. Whitter, G. F. Lundell, D. F. Veber, P. S. Anderson, R. S. L. Chang, V. J. Lotti, D. J. Cerino, T. B. Chen, P. J. Kling, K. A. Kunkel, J. P. Springer, and J. Hirshfield
Abstract image for BioChemistry
JOURNAL OF MEDICINAL CHEMISTRY

1,8-Naphthyridine Derivatives. A New Class of Chemotherapeutic Agents

George Y. Lesher, Ernest J. Froelich, Monte D. Gruett, John Hays. Bailey, and R. Pauline. Brundage
ACS LEGACY ARCHIVES

Unlock timeless value

Legacy Archives includes all ACS journal content published through 1995. That includes more than 460,000 articles spanning 117 years of scientific research.

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