JASMS | Ion Mobility

The Journal of the American Society for Mass Spectrometry covers all aspects of mass spectrometry, including fields of scientific inquiry in which mass spectrometry can play a role.

Here, we showcase a selection of highly cited articles in the area of ion mobility, published in 2019 and 2020, that researchers have been reading, sharing, and citing.

Click on the buttons below to explore articles in the following areas:

MS/ Ion Mobility for Peptide, Protein, and Oligonucleotide Characterization

MS/ Ion Mobility Instrumentation, Theory, and Operating Parameters

MS/ Ion Mobility for Studying Sprays, Solvation, Clusters, and for MS Imaging

MS/ Ion Mobility for Polymer, Saccharide, Steroid, and Small Molecule Characterization

Mass Spectrometry/ Ion Mobility for Peptide, Protein, and Oligonucleotide Characterization

Native LESA TWIMS-MSI: Spatial, Conformational, and Mass Analysis of Proteins and Protein Complexes

Oliver J. Hale, Emma K. Sisley, Rian L. Griffiths, Iain B. Styles, and Helen J. Cooper

High-Resolution Ion Mobility Separations of Isomeric Glycoforms with Variations on the Peptide and Glycan Levels

Pratima Pathak, Matthew A. Baird, and Alexandre A. Shvartsburg

Initial Protein Unfolding Events in Ubiquitin, Cytochrome c and Myoglobin Are Revealed with the Use of 213 nm UVPD Coupled to IM-MS

Alina Theisen, Rachelle Black, Davide Corinti,

Jeffery M. Brown, Bruno Bellina, and Perdita E. Barran

Conditions for Analysis of Native Protein Structures Using Uniform Field Drift Tube Ion Mobility Mass Spectrometry and Characterization of Stable Calibrants for TWIM-MS

Julian A. Harrison, Celine Kelso, Tara L. Pukala, and

Jennifer L. Beck

Native Mass Spectrometry, Ion Mobility, Electron-Capture Dissociation, and Modeling Provide Structural Information for Gas-Phase Apolipoprotein E Oligomers

Hanliu Wang, Joseph Eschweiler, Weidong Cui, Hao Zhang, Carl Frieden, Brandon T. Ruotolo, and Michael L. Gross

Solvent Mediation of Peptide Conformations: Polyproline Structures in Water, Methanol, Ethanol, and 1-Propanol as Determined by Ion Mobility Spectrometry-Mass Spectrometry

Tarick J. El-Baba, Daniel R. Fuller, David A. Hales,

David H. Russell, and David E. Clemmer

Generation of Charge-Reduced Ions of Membrane Protein Complexes for Native Ion Mobility Mass Spectrometry Studies

John W. Patrick and Arthur Laganowsky

Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator

Michael Nshanian, Carter Lantz, Piriya Wongkongkathep, Thomas Schrader, Frank-Gerrit Klärner, Anika Blümke, Clément Despres, Michael Ehrmann, Caroline Smet-Nocca, Gal Bitan, and Joseph A. Loo

Native Ion Mobility Mass Spectrometry: When Gas-Phase Ion Structures Depend on the Electrospray Charging Process

Nina Khristenko, Jussara Amato, Sandrine Livet,

Bruno Pagano, Antonio Randazzo, and Valérie Gabelica

On the Preservation of Non-covalent Peptide Assemblies in a Tandem-Trapped Ion Mobility Spectrometer-Mass Spectrometer (TIMS-TIMS-MS)

Samuel R. Kirk, Fanny C. Liu, Tyler C. Cropley,

Hunter R. Carlock, and Christian Bleiholder

Mass Spectrometry Characterization of Higher Order Structural Changes Associated with the Fc-glycan Structure of the NISTmAb Reference Material, RM 8761

Kate Groves, Adam Cryar, Simon Cowen, Alison E. Ashcroft, and Milena Quaglia

Rapid Determination of Activation Energies for Gas-Phase Protein Unfolding and Dissociation in a Q-IM-ToF Mass Spectrometer

Micah T. Donor, Samantha O. Shepherd, and James S. Prell

Substance P in Solution: Trans-to-Cis Configurational Changes of Penultimate Prolines Initiate Non-enzymatic Peptide Bond Cleavages

Christopher R. Conant, Daniel R. Fuller, Tarick J. El-Baba, Zhichao Zhang, David H. Russell, and David E. Clemmer

Mass Spectrometry/ Ion Mobility Instrumentation, Theory, and Operating Parameters

Validation of Calibration Parameters for Trapped Ion Mobility Spectrometry

Cameron N. Naylor, Tobias Reinecke, Mark E. Ridgeway, Melvin A. Park, and Brian H. Clowers

Ion Mobility Spectrometry: Fundamental Concepts, Instrumentation, Applications, and the Road Ahead

James N. Dodds and Erin S. Baker

Development and Evaluation of a Reverse-Entry Ion Source Orbitrap Mass Spectrometer

Michael L. Poltash, Jacob W. McCabe, John W. Patrick,

Arthur Laganowsky, and David H. Russell

Evaluating Separation Selectivity and Collision Cross Section Measurement Reproducibility in Helium, Nitrogen, Argon, and Carbon Dioxide Drift Gases for Drift Tube Ion Mobility–Mass Spectrometry

Caleb B. Morris, Jody C. May, Katrina L. Leaptrot, and

John A. McLean

Negative Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS)

Maria Allers, Ansgar T. Kirk, Bennet Timke, Duygu Erdogdu, Walter Wissdorf, Thorsten Benter, and Stefan Zimmermann

A Novel Ion Pseudo-trapping Phenomenon within Traveling Wave Ion Guides

Sugyan M. Dixit, Keith Richardson, David Langridge,

Kevin Giles, and Brandon T. Ruotolo

A First Principle Model of Differential Ion Mobility: the Effect of Ion-Solvent Clustering

Alexander Haack, Jeff Crouse, Femke-Jutta Schlüter,

Thorsten Benter, and W. Scott Hopkins

How Hot Are Your Ions in Differential Mobility Spectrometry?

Christian Ieritano, Joshua Featherstone, Alexander Haack, Mircea Guna, J. Larry Campbell, and W. Scott Hopkins

Positive Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS)

Maria Allers, Ansgar T. Kirk, Manuel Eckermann,

Christoph Schaefer, Duygu Erdogdu, Walter Wissdorf, Thorsten Benter, and Stefan Zimmermann

Evaluation of Trapped Ion Mobility Spectrometry Source Conditions Using Benzylammonium Thermometer Ions

Cameron N. Naylor, Mark E. Ridgeway, Melvin A. Park, and Brian H. Clowers

Mass Spectrometry/ Ion Mobility for Studying Sprays, Solvation, Clusters, and for Mass Spectrometry Imaging

Analyzing Positive Reactant Ions in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) by HiKE-IMS–MS

Maria Allers, Ansgar T. Kirk, Nikolaj von Roßbitzky,

Duygu Erdogdu, Robin Hillen, Walter Wissdorf,

Thorsten Benter, and Stefan Zimmermann

Ion Mobility-Mass Spectrometry Imaging Workflow

Daniela Mesa Sanchez, Steve Creger, Veerupaksh Singla, Ruwan T. Kurulugama, John Fjeldsted, and Julia Laskin

Coupling IR-MALDESI with Drift Tube Ion Mobility-Mass Spectrometry for High-Throughput Screening and Imaging Applications

Måns Ekelöf, James Dodds, Sitora Khodjaniyazova,

Kenneth P. Garrard, Erin S. Baker, and David C. Muddiman

Fundamental Studies of New Ionization Technologies and Insights from IMS-MS

Sarah Trimpin, Ellen D. Inutan, Santosh Karki,

Efstathios A. Elia, Wen-Jing Zhang, Steffen M. Weidner, Darrell D. Marshall, Khoa Hoang, Chuping Lee,

Eric T. J. Davis, Veronica Smith, Anil K. Meher,

Mario A. Cornejo, Gregory W. Auner, and Charles N. McEwen

Pulsed Nano-ESI: Application in Ion Mobility-MS and Insights into Spray Dynamics

William P. McMahon, Rohan Dalvi, Joseph E. Lesniewski,

Zara Y. Hall, and Kaveh Jorabchi

Preferential Ion Microsolvation in Mixed-Modifier Environments Observed Using Differential Mobility Spectrometry

Neville J. A. Coughlan, Chang Liu, Michael J. Lecours,

J. Larry Campbell, and W. Scott Hopkins

Effect of Basicity and Structure on the Hydration of Protonated Molecules, Proton-Bound Dimer and Cluster Formation: An Ion Mobility-Time of Flight Mass Spectrometry and Theoretical Study

Younes Valadbeigi, Vahideh Ilbeigi, Bartosz Michalczuk,

Martin Sabo, and Stefan Matejcik

Mass Spectrometry/ Ion Mobility for Polymer, Saccharide, Steroid, and Small Molecule Characterization

Cyclic Ion Mobility Mass Spectrometry Distinguishes Anomers and Open-Ring Forms of Pentasaccharides

Jakub Ujma, David Ropartz, Kevin Giles, Keith Richardson, David Langridge, Jason Wildgoose, Martin Green, and

Steven Pringle

Separation and Identification of Glycan Anomers Using Ultrahigh-Resolution Ion-Mobility Spectrometry and Cryogenic Ion Spectroscopy

Stephan Warnke, Ahmed Ben Faleh, Valeriu Scutelnic, and Thomas R. Rizzo

Chemical Fingerprinting of Olive Oils by Electrospray Ionization-Differential Mobility Analysis-Mass Spectrometry: A New Alternative to Food Authenticity Testing

María-Ysabel Piñero, Mario Amo-González,

Rafael Delgado Ballesteros, Leticia Ruiz Pérez,

Gonzalo Fernández de la Mora, and Lourdes Arce

Rapid and Sensitive Drug Quantification in Tissue Sections Using Matrix Assisted Laser Desorption Ionization-Ion Mobility-Mass Spectrometry Profiling

Margaux Fresnais, Alexander Muck, Marius Majewsky,

Britta Statz, Sonja Krausert, Julia Benzel, David Castel, Ludivine Le Dret, Stefan Pfister, Walter E. Haefeli,

Jürgen Burhenne, and Rémi Longuespée

Measuring Electronic Spectra of Differential Mobility-Selected Ions in the Gas Phase

Neville J. A. Coughlan, Patrick J. J. Carr, Stephen C. Walker, Ce Zhou, Mircea Guna, J. Larry Campbell, and

W. Scott Hopkins

Ion Mobility Spectrometry and Tandem Mass Spectrometry Analysis of Estradiol Glucuronide Isomers

Alana L. Rister and Eric D. Dodds

Discrimination of Regioisomeric and Stereoisomeric Saponins from Aesculus hippocastanum Seeds by Ion Mobility Mass Spectrometry

Emmanuel Colson, Corentin Decroo, Dale Cooper-Shepherd, Guillaume Caulier, Céline Henoumont, Sophie Laurent,

Julien De Winter, Patrick Flammang, Martin Palmer,

Jan Claereboudt, and Pascal Gerbaux

Ozone-Induced Cleavage of Endocyclic C═C Double Bonds within Steroid Epimers Produces Unique Gas-Phase Conformations

Samuel W. Maddox, Robert H. Fraser Caris, Kristie L. Baker, Aurora Burkus-Matesevac, Roberto Peverati, and

Christopher D. Chouinard

Understanding Nontraditional Differential Mobility Behavior: A Case Study of the Tricarbastannatrane Cation, N(CH₂CH₂CH₂)₃Sn⁺

Jeff Crouse, Alexander Haack, Thorsten Benter, and

W. Scott Hopkins

Improved Identification of Isomeric Steroids Using the Paternò-Büchi Reaction with Ion Mobility-Mass Spectrometry

Samuel W. Maddox, Stine S.H. Olsen, Diana C. Velosa,

Aurora Burkus-Matesevac, Roberto Peverati, and

Christopher D. Chouinard

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